Which ETFs own SYRE?
Spyre Therapeutics, Inc. · Healthcare · Biotechnology · US — 84 ETFs hold it, worth $1.20B across 11.74M shares.
Holdings as of Aug 27, 2026 — portfolio reporting dates from the data provider; not live positions.
| # | ETF | Weight | Shares | Value | ETF AUM | Category | Today | |
|---|---|---|---|---|---|---|---|---|
| 1 | LFSC F/M Emerald Life Sciences Innovation ETF | 7.73% | 94.68K | $10.2M | $74.7M | Artificial Intelligence | +0.41% | |
| 2 | PTH Invesco Dorsey Wright Healthcare… | 2.06% | 51.58K | $5.6M | $280.3M | Healthcare | +0.43% | |
| 3 | XBI State Street SPDR S&P Biotech ETF | 1.26% | 1.43M | $141.9M | $11.92B | Biotech | +0.37% | |
| 4 | MMSC First Trust Multi-Manager Small Cap… | 1.19% | 5.78K | $622.5K | $52.4M | Us Small Cap | +0.66% | |
| 5 | FTXH First Trust Nasdaq Pharmaceuticals ETF | 1.05% | 105.97K | $11.4M | $1.08B | Healthcare | -0.52% | |
| 6 | GDOC Goldman Sachs Future Health Care Equity… | 0.91% | 1.69K | $182.2K | $20.2M | Technology | 0.00% | |
| 7 | BBC Virtus Biotech Clinical Trials ETF | 0.81% | 3.85K | $414.7K | $53.0M | Biotech | +0.90% | |
| 8 | JDOC JPMorgan Healthcare Leaders ETF | 0.79% | 710 | $75.6K | $9.6M | Biotech | -0.61% | |
| 9 | SGRW Harbor Active Small Cap Growth ETF… | 0.76% | 2.02K | $218.2K | $29.6M | Us Small Cap | +0.44% | |
| 10 | GSC Goldman Sachs Small Cap Equity ETF | 0.72% | 19.45K | $2.1M | $280.1M | Us Small Cap | +0.51% | |
| 11 | DWAS Invesco Dorsey Wright SmallCap Momentum… | 0.67% | 27.00K | $2.9M | $430.6M | Us Small Cap | +0.75% | |
| 12 | IBBQ Invesco Nasdaq Biotechnology ETF | 0.60% | 5.11K | $550.4K | $95.8M | Biotech | -0.11% | |
| 13 | IBB iShares Biotechnology ETF | 0.57% | 576.57K | $61.9M | $10.84B | Biotech | +0.04% | |
| 14 | ESSC Eventide Small Cap ETF | 0.53% | 2.02K | $192.0K | $36.0M | Us Small Cap | +0.43% | |
| 15 | FDMO Fidelity Momentum Factor ETF | 0.50% | 42.29K | $4.5M | $903.7M | Momentum | +0.08% | |
| 16 | FMED Fidelity Disruptive Medicine ETF | 0.50% | 2.40K | $258.7K | $45.5M | Healthcare | +0.32% | |
| 17 | SCDS JPMorgan Fundamental Data Science Small… | 0.49% | 423 | $45.0K | $9.9M | Healthcare | +0.22% | |
| 18 | IWO iShares Russell 2000 Growth ETF | 0.49% | 697.03K | $74.8M | $15.19B | Us Small Cap | +0.53% | |
| 19 | VTWG Vanguard Russell 2000 Growth ETF | 0.46% | 80.48K | $7.9M | $1.70B | Us Small Cap | +0.46% | |
| 20 | OPTZ Optimize Strategy Index ETF | 0.41% | 25.79K | $860.2K | $239.9M | — | -0.34% | |
| 21 | CGMM Capital Group U.S. Small and Mid Cap ETF | 0.39% | 126.27K | $13.5M | $3.05B | Us Mid Cap | +0.08% | |
| 22 | STXK Strive Small-Cap ETF | 0.35% | 2.83K | $301.0K | $87.1M | Us Small Cap | +0.19% | |
| 23 | TNXT T. Rowe Price Innovation Leaders ETF | 0.33% | 571 | $61.5K | $18.6M | Developed Markets | +1.09% | |
| 24 | BBSC JPMorgan BetaBuilders U.S. Small Cap… | 0.32% | 22.18K | $2.4M | $753.4M | Us Small Cap | +0.21% | |
| 25 | KBFR Innovator U.S. Small Cap Managed 10… | 0.31% | 320 | $34.1K | $11.1M | Buffer | 0.00% | |
| 26 | BIB ProShares Ultra Nasdaq Biotechnology | 0.30% | 2.97K | $316.3K | $107.7M | Biotech | -0.09% | |
| 27 | RESM Columbia Research Enhanced Small Cap ETF | 0.27% | 151 | $16.3K | $6.1M | Us Small Cap | 0.00% | |
| 28 | PWS Pacer WealthShield ETF | 0.26% | 614 | $66.2K | $25.0M | — | +0.24% | |
| 29 | LABU Direxion Daily S&P Biotech Bull 3X… | 0.26% | 53.27K | $5.7M | $680.2M | Biotech | +1.05% | |
| 30 | RFLR Innovator U.S. Small Cap Managed Floor… | 0.26% | 2.31K | $246.4K | $94.0M | Financials | +0.29% | |
| 31 | IWMW iShares Russell 2000 BuyWrite ETF | 0.25% | 1.36K | $147.0K | $58.6M | Covered Call | +0.20% | |
| 32 | RSSL Global X - Russell 2000 ETF | 0.25% | 35.55K | $3.8M | $1.52B | Financials | +0.32% | |
| 33 | IWM iShares Russell 2000 ETF | 0.25% | 1.90M | $204.3M | $80.87B | Us Small Cap | +0.33% | |
| 34 | USVM VictoryShares US Small Mid Cap Value… | 0.25% | 41.86K | $4.5M | $1.79B | Us Mid Cap | -0.10% | |
| 35 | VTWO Vanguard Russell 2000 ETF | 0.23% | 417.96K | $41.1M | $17.40B | Us Small Cap | +0.34% | |
| 36 | BKMC BNY Mellon US Mid Cap Core Equity ETF | 0.21% | 12.74K | $1.4M | $664.7M | Us Mid Cap | +0.11% | |
| 37 | VFMO Vanguard U.S. Momentum Factor ETF | 0.18% | 39.68K | $3.5M | $1.80B | Momentum | +0.41% | |
| 38 | SCHA Schwab U.S. Small-Cap ETF | 0.17% | 367.75K | $39.5M | $22.94B | Us Small Cap | +0.14% | |
| 39 | JKL iShares Morningstar Small-Cap Value ETF | 0.17% | 10.94K | $1.2M | $710.3M | Us Small Cap | +0.03% | |
| 40 | ISCV iShares Morningstar Small Cap Value ETF | 0.17% | 10.94K | $1.2M | $704.0M | Us Small Cap | -0.49% | |
| 41 | TMSL T. Rowe Price Small-Mid Cap ETF | 0.16% | 46.04K | $4.9M | $2.98B | Us Mid Cap | -0.09% | |
| 42 | GSSC Goldman Sachs ActiveBeta U.S. Small Cap… | 0.16% | 16.45K | $1.8M | $1.10B | Us Small Cap | +0.24% | |
| 43 | JKJ iShares Morningstar Small-Cap ETF | 0.13% | 3.45K | $371.4K | $292.0M | Financials | 0.00% | |
| 44 | ISCB iShares Morningstar Small-Cap ETF | 0.13% | 3.45K | $371.4K | $289.6M | Us Small Cap | +0.18% | |
| 45 | ESML iShares ESG Aware MSCI USA Small-Cap ETF | 0.11% | 28.98K | $3.1M | $2.90B | Us Small Cap | +0.13% | |
| 46 | SMMD iShares Russell 2500 ETF | 0.10% | 36.76K | $3.9M | $3.83B | Financials | +0.25% | |
| 47 | UWM ProShares - Ultra Russell2000 | 0.10% | 2.33K | $248.5K | $253.6M | Developed Markets | +0.59% | |
| 48 | URTY ProShares - UltraPro Russell2000 | 0.09% | 3.02K | $322.0K | $336.4M | Developed Markets | +0.88% | |
| 49 | JKK iShares Morningstar Small-Cap Growth ETF | 0.09% | 8.79K | $943.5K | $1.01B | Us Small Cap | +1.48% | |
| 50 | ISCG iShares Morningstar Small-Cap Growth ETF | 0.09% | 8.79K | $943.5K | $1.00B | Us Small Cap | +0.22% | |
| 51 | VXF Vanguard Extended Market ETF | 0.09% | 889.66K | $87.5M | $93.70B | — | +0.58% | |
| 52 | SMLF iShares U.S. Small-Cap Equity Factor ETF | 0.09% | 36.93K | $3.9M | $4.28B | Us Small Cap | +0.22% | |
| 53 | PRFZ Invesco RAFI US 1500 Small-Mid ETF | 0.08% | 22.59K | $2.4M | $2.85B | Financials | +0.39% | |
| 54 | VBR Vanguard Morningstar Small-Cap Value ETF | 0.08% | 570.60K | $56.1M | $68.30B | Us Small Cap | -0.21% | |
| 55 | FHLC Fidelity MSCI Health Care Index ETF | 0.08% | 26.84K | $2.9M | $3.29B | Healthcare | -0.59% | |
| 56 | VHT Vanguard Health Care ETF | 0.08% | 170.25K | $16.7M | $20.90B | Healthcare | -0.61% | |
| 57 | SMMV iShares MSCI USA Small-Cap Min Vol… | 0.07% | 2.04K | $213.9K | $291.0M | Us Small Cap | -0.19% | |
| 58 | AVIE Avantis Inflation Focused Equity ETF | 0.07% | 85 | $9.2K | $13.0M | — | -0.79% | |
| 59 | DFMC U.S. Micro Cap Portfolio ETF | 0.06% | 46.12K | $4.9M | $7.93B | — | +0.15% | |
| 60 | WSML iShares MSCI World Small-Cap ETF | 0.06% | 3.51K | $376.9K | $678.9M | Financials | -0.08% | |
| 61 | VB Vanguard Morningstar Small-Cap ETF | 0.05% | 898.64K | $88.4M | $183.40B | Us Small Cap | +0.19% | |
| 62 | HDG ProShares - Hedge Replication ETF | 0.03% | 62 | $6.6K | $22.3M | Financials | 0.00% | |
| 63 | ONEQ Fidelity Nasdaq Composite Index ETF | 0.02% | 24.74K | $2.7M | $10.35B | — | +1.49% | |
| 64 | TILT Northern Trust Morningstar US Market… | 0.02% | 4.21K | $452.2K | $2.24B | — | +0.46% | |
| 65 | GUSA Goldman Sachs MarketBeta US 1000 Equity… | 0.01% | 2.59K | $276.7K | $2.40B | — | 0.00% | |
| 66 | ITOT iShares Core S&P Total U.S. Stock… | 0.01% | 103.43K | $11.1M | $97.14B | — | +0.71% | |
| 67 | SCHB Schwab U.S. Broad Market ETF | 0.01% | 46.20K | $5.0M | $44.58B | — | +0.69% | |
| 68 | VTI Vanguard Morningstar Total Stock Market… | 0.01% | 2.49M | $244.9M | $2.30T | Total Market | +0.67% | |
| 69 | IWV iShares Russell 3000 ETF | 0.01% | 19.91K | $2.1M | $20.22B | — | +0.68% | |
| 70 | VTHR Vanguard Russell 3000 ETF | 0.01% | 6.13K | $602.7K | $6.10B | — | +0.55% | |
| 71 | GTPE Goldman Sachs MSCI World Private Equity… | 0.01% | 28 | $3.0K | $31.1M | Developed Markets | +0.57% | |
| 72 | ITDH iShares LifePath Target Date 2060 ETF | 0.01% | 32 | $3.5K | $41.6M | Developed Markets | +0.25% | |
| 73 | ITDI iShares LifePath Target Date 2065 ETF | 0.01% | 22 | $2.4K | $28.6M | Developed Markets | +0.37% | |
| 74 | ITDJ iShares LifePath Target Date 2070 ETF | 0.01% | 13 | $1.4K | $16.1M | Developed Markets | +0.20% | |
| 75 | ITDG iShares LifePath Target Date 2055 ETF | 0.01% | 47 | $5.0K | $61.4M | Developed Markets | +0.31% | |
| 76 | ITDF iShares LifePath Target Date 2050 ETF | 0.01% | 64 | $6.9K | $90.0M | Developed Markets | +0.31% | |
| 77 | ITDE iShares LifePath Target Date 2045 ETF | 0.01% | 57 | $6.2K | $95.7M | Developed Markets | +0.20% | |
| 78 | ITDD iShares LifePath Target Date 2040 ETF | 0.01% | 54 | $5.8K | $111.4M | Developed Markets | +0.29% | |
| 79 | ITDC iShares LifePath Target Date 2035 ETF | 0.00% | 40 | $4.3K | $114.1M | Developed Markets | +0.11% | |
| 80 | AVLC Avantis U.S. Large Cap Equity ETF | 0.00% | 285 | $30.6K | $1.46B | Us Large Cap | +0.34% | |
| 81 | SPGM State Street SPDR Portfolio MSCI Global… | 0.00% | 329 | $34.9K | $1.76B | Developed Markets | +0.38% | |
| 82 | AVTM Avantis Total Equity Markets ETF 1 | 0.00% | 72 | $7.7K | $792.6M | Active | +0.19% | |
| 83 | AVUS Avantis U.S. Equity ETF | 0.00% | 303 | $32.5K | $14.41B | — | +0.28% | |
| 84 | IALT iShares Systematic Alternatives Active… | -0.02% | -12.31K | -$1.3M | $5.62B | Developed Markets | +0.45% |
Coverage reflects the ETF portfolios loaded in our database; very small funds may not be swept yet. Market data delayed approximately 15–20 minutes unless otherwise indicated.