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Biotechnology ETFs

Biotechnology-focused funds. 35 funds · $29.78B combined assets · median expense ratio 0.65%.

# ETF Price Today ExpenseYield (TTM)YTD1Y
1 XBI State Street SPDR S&P Biotech ETF 156.95 -1.53% 0.35%0.36% +30.71% +67.80%
2 IBB iShares Biotechnology ETF 203.23 -1.10% 0.44%0.20% +21.76% +43.76%
3 FBT First Trust NYSE Arca Biotechnology Index Fund 263.38 -0.82% 0.55% +28.58% +49.36%
4 PBPH Portfolio Building Block World Pharma and… 28.04 +0.02% 0.13%0.08% +11.07%
5 XPH State Street SPDR S&P Pharmaceuticals ETF 68.77 -0.80% 0.35%0.48% +23.76% +45.42%
6 LABU Direxion Daily S&P Biotech Bull 3X Shares 264.95 -5.04% 0.96%0.36% +75.05% +243.62%
7 BBH VanEck Biotech ETF 229.10 -0.91% 0.35%0.41% +22.17% +37.04%
8 PBE Invesco Biotechnology & Genome ETF 93.44 -1.23% 0.59%1.64% +15.16% +33.33%
9 PINK Simplify Health Care ETF 38.75 -0.84% 0.51%0.64% +6.78% +24.70%
10 SBIO ALPS Medical Breakthroughs ETF 63.85 -2.07% 0.50% +27.29% +77.66%
11 CANC Tema Oncology ETF 42.16 -0.85% 0.99%0.05% +22.47% +55.41%
12 BBP Virtus Biotech ETF 103.95 -1.49% 0.34% +31.96% +50.15%
13 BIB ProShares Ultra Nasdaq Biotechnology 109.57 -2.87% 1.19%0.29% +41.40% +92.37%
14 IBBQ Invesco Nasdaq Biotechnology ETF 34.46 -1.37% 0.19%0.73% +22.98% +44.99%
15 RXL ProShares Ultra Health Care 57.38 +0.10% 1.07%1.24% +10.63% +35.60%
16 GNOM Global X - Genomics & Biotechnology ETF 61.42 -2.12% 0.50%1.03% +38.04% +68.28%
17 SURI Simplify Propel Opportunities ETF 19.70 -0.36% 2.82%13.74% +18.70% +25.63%
18 LABD Direxion Daily S&P Biotech Bear 3X ETF 7.37 +5.21% 1.08%5.93% -66.76% -85.51%
19 HRTS Tema Heart & Health ETF 36.30 -0.64% 0.99%1.29% +3.51% +18.83%
20 BBC Virtus Biotech Clinical Trials ETF 50.51 -1.94% 0.65%1.27% +33.58% +109.39%
21 IEIH iShares Evolved U.S. Innovative Healthcare ETF 34.13 0.00% 0.18% -3.74% -7.92%
22 BTEC Principal Healthcare Innovators ETF 39.49 +1.02% 0.42% +8.70% +18.51%
23 UBIO ProShares UltraPro Nasdaq Biotechnology 17.77 0.00% 0.95% -45.67% -44.01%
24 CNCR Loncar Cancer Immunotherapy ETF 9.02 +1.58% 0.79% -26.73% -38.81%
25 SLIM The Obesity ETF 33.25 -8.06% 0.35% -13.72% -7.24%
26 CHNA Loncar China BioPharma ETF 13.53 -0.07% 0.79% -47.95% -33.94%
27 JDOC JPMorgan Healthcare Leaders ETF 60.94 -0.48% 0.65%0.84% +5.84% +17.34%
28 IBBJ Defiance Nasdaq Junior Biotechnology ETF 29.87 -0.07% 0.45% -13.27% -8.46%
29 TBXU Direxion Daily Biotech Top 5 Bull 2X ETF 40.15 -1.22% 6.27%1.30% +29.23%
30 KMED KraneShares Emerging Markets Healthcare Index… 18.81 -2.72% 0.79%
31 BIS ProShares - UltraShort Nasdaq Biotechnology 11.89 +2.16% 3.20%3.97% -38.61% -57.21%
32 SYNB Putnam BioRevolution ETF 31.61 -0.37% 0.70% +6.90% +4.36%
33 CHB Global X China Biotech Innovation ETF 6.64 -0.38% 0.65% -18.02% -33.20%
34 BIOY GraniteShares YieldBOOST Biotech ETF 20.79 -1.12% 1.07%22.26%
35 XBIX Corgi U.S. Biotech 2x Daily ETF 36.99 -2.97% 0.45%

Market data delayed approximately 15–20 minutes unless otherwise indicated. Category membership is an ETF Explorer classification — see Methodology.

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