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Which ETFs own SEPN?

Septerna Inc · Healthcare · Biotechnology · US — 65 ETFs hold it, worth $133.2M across 3.62M shares.

Holdings as of Oct 10, 2026 · portfolio reporting dates from the data provider; not live positions.

#ETFWeight SharesValueETF AUM CategoryToday
1 XPH State Street SPDR S&P Pharmaceuticals… 1.85% 231.02K $8.5M $461.6M Biotech +1.60%
2 BBC Virtus Biotech Clinical Trials ETF 0.79% 8.83K $325.7K $41.0M Biotech +2.08%
3 FYC First Trust Small Cap Growth AlphaDEX… 0.62% 218.57K $8.4M $1.33B Us Small Cap +1.35%
4 MMSC First Trust Multi-Manager Small Cap… 0.60% 8.23K $316.0K $51.7M Us Small Cap +1.59%
5 PILL Direxion Daily Pharmaceutical & Medical… 0.42% 6.03K $222.5K $16.3M Healthcare +5.15%
6 SYZ Lazard US Systematic Small Cap Equity… 0.33% 5.63K $207.6K $66.3M Us Small Cap +0.43%
7 FYX First Trust Small Cap Core AlphaDEX Fund 0.31% 107.30K $4.1M $1.34B Us Small Cap +0.28%
8 AFSM First Trust Active Factor Small Cap ETF 0.28% 9.53K $365.6K $129.3M Us Small Cap +0.29%
9 SQLV Royce Quant Small-Cap Quality Value ETF 0.20% 2.11K $77.9K $38.1M Us Small Cap -0.04%
10 IHE iShares U.S. Pharmaceuticals ETF 0.20% 82.87K $3.1M $1.52B Healthcare +1.24%
11 FSCC Federated Hermes MDT Small Cap Core ETF 0.16% 18.99K $700.6K $420.1M Us Small Cap +0.53%
12 ACSG American Century Small Cap Growth… 0.16% 2.23K $82.1K $51.4M Us Small Cap +1.24%
13 JPSE JPMorgan Diversified Return U.S. Small… 0.13% 19.95K $765.6K $571.2M Us Small Cap -0.07%
14 FAD First Trust Multi Cap Growth AlphaDEX… 0.12% 19.56K $750.4K $600.3M Growth +1.49%
15 IBBQ Invesco Nasdaq Biotechnology ETF 0.12% 3.48K $133.7K $108.3M Biotech +2.96%
16 FSML Franklin Small Cap Enhanced ETF 0.10% 4.00K $153.7K $150.4M Us Small Cap +0.48%
17 VFMO Vanguard U.S. Momentum Factor ETF 0.08% 48.86K $1.6M $1.90B Momentum +1.02%
18 IBB iShares Biotechnology ETF 0.08% 226.15K $8.3M $10.28B Biotech +3.00%
19 AVSC Avantis U.S. Small Cap Equity ETF 0.07% 61.78K $2.3M $3.06B Us Small Cap +0.03%
20 BIB ProShares Ultra Nasdaq Biotechnology 0.07% 1.79K $68.8K $93.2M Biotech +5.68%
21 GSSC Goldman Sachs ActiveBeta U.S. Small Cap… 0.06% 15.84K $584.3K $1.04B Us Small Cap +0.43%
22 FMED Fidelity Disruptive Medicine ETF 0.05% 700 $25.8K $52.3M Healthcare +2.73%
23 RESM Columbia Research Enhanced Small Cap ETF 0.05% 79 $2.9K $5.8M Us Small Cap +0.57%
24 IWO iShares Russell 2000 Growth ETF 0.04% 134.65K $5.0M $13.97B Us Small Cap +0.94%
25 VTWG Vanguard Russell 2000 Growth ETF 0.04% 16.15K $616.2K $1.70B Us Small Cap +0.91%
26 WSGE Warren Street Global Equity ETF 0.03% 478 $18.3K $61.9M Preferred Stocks +1.17%
27 RSSL Global X - Russell 2000 ETF 0.03% 10.52K $403.5K $1.41B Financials +0.21%
28 IWM iShares Russell 2000 ETF 0.03% 584.18K $21.6M $78.27B Us Small Cap +0.49%
29 IWMW iShares Russell 2000 BuyWrite ETF 0.03% 410 $15.1K $55.4M Covered Call +0.63%
30 ITWO ProShares Russell 2000 High Income ETF 0.03% 1.29K $49.5K $185.0M Covered Call +0.96%
31 VTWO Vanguard Russell 2000 ETF 0.03% 127.18K $4.9M $18.00B Us Small Cap +0.50%
32 ISCG iShares Morningstar Small-Cap Growth ETF 0.02% 6.33K $233.7K $958.5M Us Small Cap +0.73%
33 JKK iShares Morningstar Small-Cap Growth ETF 0.02% 6.33K $228.0K $960.7M Us Small Cap +1.48%
34 RB ProShares Trust - ProShares Russell… 0.02% 7 $268.59 $1.2M Buffer 0.00%
35 SCHA Schwab U.S. Small-Cap ETF 0.02% 126.63K $4.7M $21.73B Us Small Cap +0.40%
36 VTWV Vanguard Russell 2000 Value ETF 0.02% 6.84K $261.1K $1.40B Us Small Cap -0.13%
37 OMFS Invesco Russell 2000 Dynamic… 0.02% 1.22K $47.0K $264.6M Us Small Cap +0.30%
38 PRFZ Invesco RAFI US 1500 Small-Mid ETF 0.02% 11.72K $449.7K $2.65B Financials +0.64%
39 ISCB iShares Morningstar Small-Cap ETF 0.01% 906 $36.00 $274.0M Us Small Cap +0.83%
40 URTY ProShares - UltraPro Russell2000 0.01% 907 $34.8K $279.8M Developed Markets +1.37%
41 VXF Vanguard Extended Market ETF 0.01% 266.57K $10.2M $95.40B — +0.80%
42 DFMC U.S. Micro Cap Portfolio ETF 0.01% 20.44K $754.2K $7.56B — +0.20%
43 JKJ iShares Morningstar Small-Cap ETF 0.01% 720 $26.00 $278.3M Financials 0.00%
44 MSML iShares MSCI USA Small-Cap ETF 0.01% 720 $26.00 $271.8M Us Small Cap +0.64%
45 UWM ProShares - Ultra Russell2000 0.01% 536 $20.6K $225.1M Developed Markets +0.96%
46 VHT Vanguard Health Care ETF 0.01% 51.63K $2.0M $22.00B Healthcare +1.64%
47 FHLC Fidelity MSCI Health Care Index ETF 0.01% 8.56K $316.0K $3.54B Healthcare +1.61%
48 ONEQ Fidelity Nasdaq Composite Index ETF 0.01% 17.47K $644.6K $10.94B — +0.63%
49 HDG ProShares - Hedge Replication ETF 0.00% 27 $1.0K $22.5M Financials 0.00%
50 DFAS Dimensional - US Small Cap ETF 0.00% 37.36K $1.4M $33.87B Us Small Cap +0.32%
51 MSSM Morgan Stanley Pathway Funds -… 0.00% 636 $24.4K $688.8M Us Mid Cap +0.92%
52 IWN iShares Russell 2000 Value ETF 0.00% 69.10K $2.00 $13.85B Us Small Cap -0.04%
53 AVSU Avantis Responsible U.S. Equity ETF 0.00% 205 $7.6K $491.0M — +0.24%
54 VTI Vanguard Morningstar Total Stock Market… 0.00% 927.66K $35.4M $2.30T Total Market +0.63%
55 IWV iShares Russell 3000 ETF 0.00% 6.95K $256.3K $20.45B — +0.63%
56 AVUS Avantis U.S. Equity ETF 0.00% 4.93K $182.0K $14.77B — +0.35%
57 SCHB Schwab U.S. Broad Market ETF 0.00% 14.78K $549.5K $45.06B — +0.61%
58 ITOT iShares Core S&P Total U.S. Stock… 0.00% 29.85K $1.1M $97.48B — +0.64%
59 VTHR Vanguard Russell 3000 ETF 0.00% 1.87K $71.2K $6.40B — +0.62%
60 DFAU Dimensional - US Core Equity Market ETF 0.00% 2.96K $109.0K $13.12B — +0.49%
61 AVUQ Avantis U.S. Quality ETF 0.00% 90 $3.3K $380.8M — +0.50%
62 DFAC Dimensional - US Core Equity 2 ETF 0.00% 16.00K $590.5K $88.60B — +0.49%
63 AVTM Avantis Total Equity Markets ETF 1 0.00% 71 $2.6K $790.1M Active +0.56%
64 DCOR U.S. Core Equity 1 Portfolio ETF Class… 0.00% 2.07K $76.4K $45.59B — +0.44%
65 DFUS Dimensional U.S. Equity ETF 0.00% 198 $7.3K $21.65B — +0.62%

Coverage reflects the ETF portfolios loaded in our database; very small funds may not be swept yet. Market data delayed approximately 15–20 minutes unless otherwise indicated.

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