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Biotechnology ETFs

Biotechnology-focused funds. 34 funds · $30.58B combined assets · median expense ratio 0.65%.

# ETF Price Today ExpenseYield (TTM)YTD1Y
1 XBI State Street SPDR S&P Biotech ETF 168.39 -0.42% 0.35%0.34% +38.69% +90.45%
2 IBB iShares Biotechnology ETF 215.23 -0.54% 0.44%0.19% +28.22% +57.88%
3 FBT First Trust NYSE Arca Biotechnology Index Fund 272.07 -0.11% 0.55% +31.89% +59.18%
4 PBPH Portfolio Building Block World Pharma and… 29.33 -1.67% 0.13%0.08% +18.01%
5 LABU Direxion Daily S&P Biotech Bull 3X Shares 331.59 -1.18% 0.96%0.30% +110.52% +400.66%
6 XPH State Street SPDR S&P Pharmaceuticals ETF 72.81 -1.03% 0.35%0.46% +31.35% +58.39%
7 BBH VanEck Biotech ETF 242.67 -0.33% 0.35%0.39% +28.22% +46.62%
8 PBE Invesco Biotechnology & Genome ETF 98.09 -0.65% 0.58%1.57% +20.18% +46.10%
9 PINK Simplify Health Care ETF 40.14 -0.15% 0.51%0.62% +9.84% +34.36%
10 SBIO ALPS Medical Breakthroughs ETF 69.66 -0.95% 0.50% +37.31% +104.63%
11 CANC Tema Oncology ETF 44.84 -1.03% 0.99%0.04% +29.16% +67.46%
12 BBP Virtus Biotech ETF 108.66 -0.30% 0.34% +35.97% +60.83%
13 BIB ProShares Ultra Nasdaq Biotechnology 123.98 -1.05% 1.19%0.26% +55.40% +121.91%
14 GNOM Global X - Genomics & Biotechnology ETF 67.35 -0.74% 0.50%0.96% +49.26% +84.99%
15 IBBQ Invesco Nasdaq Biotechnology ETF 36.57 -0.62% 0.19%0.70% +29.58% +58.28%
16 RXL ProShares Ultra Health Care 62.43 -1.95% 1.07%1.11% +22.90% +55.53%
17 SURI Simplify Propel Opportunities ETF 20.47 +1.11% 2.82%13.43% +21.38% +28.63%
18 LABD Direxion Daily S&P Biotech Bear 3X ETF 5.96 +1.02% 1.08%7.04% -71.98% -90.08%
19 HRTS Tema Heart & Health ETF 38.47 -0.73% 0.99%1.22% +9.85% +32.86%
20 BBC Virtus Biotech Clinical Trials ETF 55.15 -1.09% 0.65%1.19% +43.02% +141.04%
21 IEIH iShares Evolved U.S. Innovative Healthcare ETF 34.13 0.00% 0.18% -3.74% -7.92%
22 BTEC Principal Healthcare Innovators ETF 39.49 +1.02% 0.42% +8.70% +18.51%
23 UBIO ProShares UltraPro Nasdaq Biotechnology 17.77 0.00% 0.95% -45.67% -44.01%
24 CNCR Loncar Cancer Immunotherapy ETF 9.02 +1.58% 0.79% -26.73% -38.81%
25 SLIM The Obesity ETF 33.25 -8.06% 0.35% -13.72% -7.24%
26 CHNA Loncar China BioPharma ETF 13.53 -0.07% 0.79% -47.95% -33.94%
27 JDOC JPMorgan Healthcare Leaders ETF 64.05 -0.93% 0.65%0.79% +11.78% +26.47%
28 IBBJ Defiance Nasdaq Junior Biotechnology ETF 29.87 -0.07% 0.45% -13.27% -8.46%
29 TBXU Direxion Daily Biotech Top 5 Bull 2X ETF 44.35 -0.61% 6.27%1.17% +43.62%
30 KMED KraneShares Emerging Markets Healthcare Index… 18.81 -2.72% 0.79%
31 BIS ProShares - UltraShort Nasdaq Biotechnology 10.65 +0.78% 3.20%4.34% -43.82% -62.65%
32 SYNB Putnam BioRevolution ETF 31.61 -0.37% 0.70% +6.90% +4.36%
33 CHB Global X China Biotech Innovation ETF 6.64 -0.38% 0.65% -18.02% -33.20%
34 BIOY GraniteShares YieldBOOST Biotech ETF 21.43 +0.23% 1.07%19.51%

Market data delayed approximately 15–20 minutes unless otherwise indicated. Category membership is an ETF Explorer classification — see Methodology.

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